Adrenacalm Cream Side Effects: What You Need to Know

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Adrenacalm cream is a product that claims to help people who suffer from stress, fatigue, and adrenal issues.

It is a liposomal topical delivery system that is applied directly to the skin, where it delivers nutrients that are essential for calming the adrenals and reducing the effects of stress.

But what are the benefits and potential side effects of using Adrenacalm cream?

In this blog post, we will explore the key ingredients, how it works, and what you need to know before trying it.

How Adrenacalm Works

Adrenacalm works by using a liposomal delivery system, which means that the active ingredients are encapsulated in tiny spheres called liposomes. These liposomes are designed to protect the ingredients from degradation and enhance their absorption through the skin. This way, the nutrients can reach the bloodstream and the target organs more effectively than oral supplements.

One of the main advantages of this approach is that it bypasses the digestive system, which can sometimes interfere with the absorption and metabolism of certain nutrients.

For example, some people may have low stomach acid, food sensitivities, or gut inflammation that can affect how well they absorb oral supplements. By applying Adrenacalm cream to the skin, these issues can be avoided and the nutrients can be delivered more efficiently.

Another advantage of using Adrenacalm cream is that it allows for more precise and personalized dosage. Depending on your needs and preferences, you can adjust the amount and frequency of application to suit your situation.

You can also apply the cream to different areas of the body, such as the neck, chest, abdomen, or inner arms, depending on where you feel the most stress or discomfort.

Key Ingredients in Adrenacalm

Adrenacalm contains several ingredients that are known to support the adrenal glands and the nervous system.

The most important one is Phosphatidylserine (PS), which is a phospholipid that is found in high concentrations in the brain and the cell membranes. PS plays a vital role in maintaining the health and function of the neurons, the communication between the cells, and the regulation of the hormones.

PS is especially helpful for counteracting the effects of stress and its impact on cortisol production. Cortisol is a hormone that is released by the adrenal glands in response to stress. It helps the body cope with stress by increasing blood sugar, blood pressure, and heart rate, and suppressing the immune system and digestion.

However, when the stress is chronic or excessive, cortisol can become too high and cause a range of problems, such as:

  • Weight gain
  • Insomnia
  • Anxiety
  • Depression
  • Memory loss
  • Brain fog
  • Inflammation
  • Immune dysfunction
  • Hormonal imbalance
  • Thyroid dysfunction

PS can help lower cortisol levels by inhibiting the enzyme that converts the precursor hormone ACTH into cortisol. This way, PS can help restore the balance between stress and relaxation hormones and improve mood, sleep, and cognitive function.

Other Ingredients

Other ingredients in Adrenacalm include:


A neurotransmitter that helps calm the nervous system and reduce anxiety and stress.

#2 L-Theanine

An amino acid that promotes relaxation and mental clarity without causing drowsiness.

#3 Magnesium

A mineral that is involved in over 300 enzymatic reactions in the body, including the production of energy, the synthesis of proteins, and the regulation of the nervous system.

Magnesium can help relax the muscles, lower blood pressure, and improve sleep quality.

#4 Zinc

A mineral that is essential for the immune system, wound healing, and growth and development.

Zinc can help support the adrenal function and the thyroid function, as well as protect the cells from oxidative stress.

#5 Vitamin B5

A vitamin that is involved in the metabolism of carbohydrates, fats, and proteins, and the synthesis of coenzyme A, which is needed for the production of energy and the adrenal hormones.

Vitamin B5 can help support the adrenal function and energy levels.

Benefits of Using Adrenacalm

By using Adrenacalm cream, you can expect to experience several benefits, such as

#1 Supporting a fatiguing adrenal response

Suppose you suffer from adrenal fatigue, which is a condition where the adrenal glands are unable to produce enough hormones to cope with the stress.

In that case, you may experience symptoms such as low energy, low blood pressure, salt cravings, and difficulty waking up.

Adrenacalm can help nourish the adrenals and restore their function, as well as balance the cortisol levels and the circadian rhythm.

#2 Improving cognitive function

If you struggle with memory, concentration, or learning, Adrenacalm can help boost your brain power and performance.

PS can help improve the communication between the brain cells, the formation of new memories, and the recall of old ones.

It can also help protect the brain from aging and degeneration and prevent cognitive decline and dementia.

#3 Regulating blood sugar and blood pressure

If you have problems with your blood sugar or blood pressure, Adrenacalm can help stabilize them and prevent spikes and crashes.

PS can help lower cortisol levels, reducing insulin resistance and the inflammation that can cause diabetes and metabolic syndrome.

Magnesium can help relax the blood vessels, lower blood pressure, and improve insulin sensitivity and glucose metabolism.

#4 Managing thyroid disorders

If you have a thyroid disorder, such as hypothyroidism or Hashimoto’s, Adrenacalm can help support your thyroid function and balance your hormones.

PS can help lower cortisol levels, which can interfere with the conversion of the inactive thyroid hormone T4 into the active thyroid hormone T3.

Zinc can help stimulate the production of the thyroid hormones and the thyroid-stimulating hormone (TSH), as well as protect the thyroid from oxidative stress and autoimmune attacks.

Side Effects of Adrenacalm

While Adrenacalm is generally considered safe and well-tolerated, it is important to note that any medication or supplement can have potential side effects, especially if used incorrectly or excessively.

Some of the possible side effects of Adrenacalm include:

#1 Allergic reactions

Some people may be allergic or sensitive to some of the ingredients in Adrenacalm, such as PS, GABA, or magnesium.

This can cause symptoms such as itching, rash, hives, swelling, or difficulty breathing.

If you experience any of these symptoms, stop using Adrenacalm and seek medical attention immediately.

#2 Gastrointestinal issues

Some people may experience digestive issues such as nausea, vomiting, diarrhea, or constipation when using Adrenacalm.

This may be due to the absorption of the ingredients through the skin, or the interaction with other medications or supplements.

To minimize this risk, start with a low dose gradually increase it, and avoid applying the cream to the abdominal area.

#3 Sleep disturbances

Some people may experience changes in their sleep patterns, such as insomnia, vivid dreams, or drowsiness when using Adrenacalm.

This may be due to the effect of the ingredients on the cortisol levels and the circadian rhythm.

To avoid this, do not apply the cream too close to bedtime, and adjust the dosage and timing according to your needs and preferences.

#4 Hormonal changes

Some people may experience changes in their hormonal levels, such as estrogen, progesterone, testosterone, or thyroid hormones when using Adrenacalm.

This may be due to the effect of the ingredients on the adrenal function and the feedback loop between the adrenals and the other endocrine glands.

To monitor this, consult with your doctor and get regular blood tests to check your hormone levels and adjust your dosage accordingly.


Adrenacalm cream is a product that can help people who suffer from stress and adrenal fatigue.

It is a liposomal topical delivery system that delivers nutrients that are essential for calming the adrenals such as PS, GABA, L-theanine, Magnesium, Zinc, and Vitamin B5.

These nutrients can help to support a fatiguing adrenal response, improve cognitive function, regulate blood sugar and blood pressure, manage thyroid disorders, and improve memory and cognition.

However, Adrenacalm cream can also have potential side effects, such as allergic reactions, drug interactions, and overdose.

Therefore, it is important to use Adrenacalm cream under the guidance of a healthcare professional, who can help you determine if it is suitable for you and how to use it safely and effectively.

The Bottom Line

We hope you enjoyed this blog post and learned something new about Adrenacalm cream’s side effects.

If you did, please share it with others who might find it helpful.

If you have any questions or comments, please leave them below.

We would love to hear from you.

Thank you for reading!

Frequently Asked Questions

How common are allergic reactions to Adrenacalm cream?

Allergic reactions to Adrenacalm cream are rare, but they can occur in people who are sensitive or allergic to any of the ingredients in the cream. Symptoms of an allergic reaction can include rash, itching, swelling, redness, and difficulty breathing. If you experience any of these symptoms, stop using the cream and seek medical attention immediately.

What are the signs of overdose from Adrenacalm cream?

Overdose from Adrenacalm cream can occur if you use more than the recommended dose of the cream. Symptoms of overdose can include nausea, vomiting, diarrhea, headache, drowsiness, and confusion. If you suspect an overdose, contact your doctor or poison control center right away.

How long can I use Adrenacalm cream?

The duration of using Adrenacalm cream depends on your condition and response to the treatment. Your doctor can advise you on how long you should use the cream, monitor your progress, and adjust your treatment as needed. Generally, you should not use the cream for longer than 12 weeks, unless directed by your doctor.


  • Hindiopedia

    Hi, I'm A. Rohman, the pen behind Hindiopedia. While I'm just a passionate blogger, my journey in the world of health and fitness has equipped me with valuable insights and a strong desire to help oth...

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